The Avengers including a Hulkbuster-suited Iron Man , the X-Men, the Fantastic Four, Juggernaut, Doctor Strange, Black Bolt, Ghost Rider, and the US Army were pitted against the Worldbreaker Hulk.
Years Later, the Illuminati ship he crashed in exploded destroying the planet and killing most of his friends and Wife.
Doomsday would win eventually, but he'd probably be KO'd a few times before hand.