Their Premier League match at Leicester on December 16 will also be in doubt, not only due to the situation in Conte's squad but because the Foxes have been hit by a less widespread Covid outbreak.
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That means any player that tests positive now will likely miss four crucial games, at least.
Per Premier League rules, a game must be played if a team has 14 players available and states that Spurs are in talks with the league about possibly postponing the game at Brighton on Sunday.
Why do we have to take the risk? The Athletic have now explained that the announcement could mean that Rennes could be considered 3-0 winners of the encounter.
In the Premier League, the 2021-22 handbook states permission will not be granted to postpone a league match if a club has 14 or more players on its squad list available.